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Ulcerative Colitis

Ulcerative colitis is one of the forms of Inflammatory Bowel Disease (IBD). It happens when the lining of the colon or rectum becomes inflamed, causing problems such as abdominal pain, rectal bleeding and diarrhoea. Ulcerative colitis is a chronic condition that requires specialist management with an experienced Gastroenterologist at the Bangalore Gastroenterology Centre.

What causes Ulcerative Colitis (UC) ?The causes of UC aren’t fully understood, but we do know that it is associated with your immune system. Ulcerative colitis seems to happen when your immune system starts attacking your own cells. Scientists believe that in ulcerative colitis, the inflammation could happen because the immune system gets confused by the good bacteria that live in your gut. One of the ways your immune system tries to defend you is by recruiting white blood cells to your gut, which causes inflammation.When you have an infection, this can help to get rid of the bad bacteria. However, if your immune system starts attacking the good bacteria that are always present in your digestive system, the immune response lasts longer than usual. The inflammation starts to cause problems for your digestion, and it keeps coming back every time your immune system is incorrectly stimulated.Another theory is that the immune system is in fact triggered by an infection. It fights off the bad bacteria or viruses, but it doesn’t stop. The immune response continues after the infection is gone, so your gut continues to suffer from inflammation.While we still don’t know exactly what causes your immune system to malfunction, we do know that there are some factors that can affect your chances of developing colitis
  • If other people in your family have IBD, you may be more likely to develop it yourself as there seems to be a genetic component
  • Lifestyle may also play a part, as ulcerative colitis is more common in developed countries such as the UK, USA, Australia
  • The incidence of Ulcerative colitis is however increasing steadily in India
How is the Diagnosis of Ulcerative Colitis made?If you’re experiencing symptoms that could be colitis, you should seek advice from a Medical Gastroenterologist particularly if you have lost weight or noticed blood in your stool. It is important to find out what is causing these problems.In order to provide a diagnosis, the Medical Gastroenterologist may need to perform the following checks:
  • A physical exam to look for abdominal tenderness or paleness caused by anaemia (low blood count)
  • A blood test to see if you are anaemic and to assess the amount of inflammation in your body
  • Testing a stool sample to rule out an infection, which could cause similar symptoms to ulcerative colitis
  • Testing the stool sample to check for inflammation.
  • A colonoscopy to examine the colon directly for inflammation
  • Lab tests on biopsies taken during colonoscopy, to confirm the presence of ulcerative colitis and help rule out Crohn’s disease
  • In some patients, CT scan to check for any serious complications of IBD
What is the treatment for Ulcerative Colitis?Unfortunately, there is not yet a cure for ulcerative colitis, so treatment will focus on preventing flare-ups from happening often and relieving the symptoms when they do. The most common way we achieve this is by using medications and keeping the colitis under control/remission.People with Ulcerative Colitis can lead a completely normal life without any changes to their diet.
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